When taken by mouth: Zinc is likely safe when used in amounts no greater than 40 mg daily. It is possibly safe when taken in larger doses, especially when used only for a short period of time. But taking doses higher than 40 mg daily might decrease how much copper the body absorbs. Taking very high doses of zinc is likely unsafe and might cause stomach pain, vomiting, and many other problems. Single doses of 10-30 grams of zinc can be fatal.

When applied to the skin: Zinc is likely safe. Using zinc on broken skin may cause burning, stinging, itching, and tingling.

When inhaled: Zinc is possibly unsafe when inhaled through the nose. It might cause permanent loss of smell. Avoid using nose sprays containing zinc. Pregnancy: Zinc is likely safe when used in the recommended amounts while pregnant. But it is likely unsafe when used in high doses. Those over 18 should not take more than 40 mg of zinc daily, and those 14-18 years old should not take more than 34 mg daily while pregnant.

Breast-feeding: Zinc is likely safe when used in the recommended amounts while breast-feeding. But zinc is possibly unsafe when used in high doses. Those over 18 years old should not take more than 40 mg of zinc daily, and those 14-18 years old should not take more than 34 mg daily while breast-feeding.

Children: Zinc is likely safe when taken by mouth appropriately in recommended amounts. Daily doses of zinc should not exceed 4 mg daily in infants 0-6 months old, 5 mg daily in infants 7-12 months old, 7 mg daily in children 1-3 years old, 12 mg daily in children 4-8 years old, 23 mg daily in children 9-13 years old, and 34 mg daily in those 14-18 years old. In infants, it is possibly unsafe to apply topical zinc to broken skin. The zinc can be absorbed through the breaks in the skin and cause serious adverse effects.

Alcohol use disorder: Long-term, excessive alcohol use may reduce the body’s ability to absorb zinc.

Surgery for weight-loss (bariatric surgery): Bariatric surgery reduces the absorption of zinc and might increase the risk for zinc deficiency. Zinc levels may need to be monitored.

Kidney disease: Low intake of zinc in the diet might increase the risk of getting kidney disease. Also, people with kidney disease who are on hemodialysis are at risk for zinc deficiency and might require zinc supplements.

Vegetarianism: Vegetarian diets are often linked with lower zinc absorption. But the body adapts over time Manufacturer of Kopcitrate (Zinc Citrate) in India

Zinc citrate is a zinc salt of citric acid. It is available as dietary supplements as a treatment of zinc deficiency and source of zinc, which is an essential trace element. Zinc citrate demonstrates effective absorption following oral administration.

Zinc Citrate is an essential trace mineral and a factor in the maintenance of good health as it supports and protects the immune system and helps the body fight against diseases. Zinc is important for tissue formation and the proper metabolism of fats, proteins, and carbohydrates.

Zinc citrate is available as dihydrate and trihydrate and is produced by complete neutralisation of citric acid with a high purity zinc source, subsequent precipitation and dehydration.

Zinc citrate is mainly used in dental care products such as toothpastes, mouthwashes and chewing gums due to its antimicrobial and anti-inflammatory effects and its ability to reduce or inhibit the formation of dental plaque and tartar. In pharmaceuticals, zinc citrate fights common colds. Zinc is increasingly used in food supplements, functional foods and beverages.

As an organic mineral source it is preferred in many applications over inorganic sources because of its superior bioavailability, physiological compatibility and nearly neutral taste compared to other zinc salts.

Among the organic zinc salts zinc citrate has one of the highest zinc content  31 %, Zinc citrate is supplied as a white to almost white powder. It is practically odourless, slightly soluble in water, soluble in diluted acid and practically insoluble in ethanol 96 %. Zinc citrate has an inverse solubility.

Zinc Citrate Tri-hydrate is used in toothpaste and mouthwash to prevent dental plaque formation and gingivitis. Zinc is also used in chew gum, candies, and mouth rinses to treat bad breath.

Zinc Citrate Di-hydrate is used in food supplements, functional foods and beverages. It is used to formulated in pharmaceuticals, and foods as a zinc supplement.

To summarize, Zinc citrate Tri-hydrate is mainly used in oral care ingredients and followed by food supplements and dietary supplements. Regulatory status, it is listed in Canada, China, Japan, Korea and Australia. It is GMP certified, ISO 9001 and ISO 14001 certified for Tri-hydrate. Zinc is an important nutrient necessary for protein synthesis, wound healing and also for tissue function.

 It becomes better at absorbing zinc and reducing zinc loss.

Moderate Interaction

Be cautious with this combination

Antibiotics (Quinolone antibiotics) interacts with ZINC

Zinc might decrease how much antibiotic the body absorbs from the gut. Taking zinc along with quinolone antibiotics might decrease the effects of these antibiotics. To avoid this interaction, take antibiotics at least 2 hours before or 4-6 hours after zinc supplements.

Antibiotics (Tetracycline antibiotics) interacts with ZINC

Zinc can decrease the amount of tetracyclines the body absorbs. Taking zinc with tetracyclines might decrease the effects of tetracyclines. To avoid this interaction, take tetracyclines 2 hours before or 4-6 hours after taking zinc supplements.

Cisplatin (Platinol-AQ) interacts with ZINC

Cisplatin is used to treat cancer. Taking zinc along with cisplatin might inactivate cisplatin therapy. But it’s not clear if this is a big concern.

Penicillamine (Cuprimine, Depen) interacts with ZINC

Zinc might decrease how much penicillamine the body absorbs. Taking zinc with penicillamine might decrease the effects of penicillamine. Take zinc and penicillamine at least 2 hours apart.

Cephalexin (Keflex) interacts with ZINC

Zinc can reduce how much cephalexin the body absorbs. This might decrease how well cephalexin works for treating infections. To avoid this interaction, take zinc 3 hours after taking cephalexin.